SAN ANTONIO – One of the most promising new approaches for fighting breast cancer took a stunning setback Thursday when a major study showed that a bone-building drug did not stop cancer from returning or extend life for most women fighting the disease.
However, the drug Zometa did seem to help certain post-menopausal women. Its maker, Novartis AG, is considering further study, but will suspend plans to expand it beyond its current use as a treatment for patients whose cancer has spread to the bone.
"Ten years of work and to have essentially a negative study is disappointing, particularly on a tremendous wave of enthusiasm for this based on some positive trials in the past," said the study's leader, Dr. Robert Coleman of the University of Sheffield in England. He presented results at a cancer conference in San Antonio.
Bone drugs called bisphosphonates, sold as Fosamax, Boniva and Actonel, have long been sold for treating osteoporosis. Those are daily pills; Zometa, sold as Reclast for osteoporosis, is given as an infusion twice a year.
Hopes that these drugs could also prevent cancer soared after a study two years ago found Zometa cut the risk of cancer recurrence by 30 percent in younger women forced into early menopause by hormone treatments they received.
GO HERE to read more.
No comments:
Post a Comment