When it comes to proven, over-the-counter solutions for easing pain and controlling a fever, acetaminophen (also called paracetamol, and best known by the brand name, Tylenol) has long been the preferred recommendation for many. It is actually the most widely used product of its kind, and with good reason. When compared to other non-prescription pain relievers and fever reducers, such as aspirin or ibuprofen, acetaminophen is considered to be much more safe — especially for young children, people with weak or compromised liver function, or blood-clotting concerns. 
The Dangers of Acetaminophen
But, not so fast. Despite being a better choice than some of the alternatives, acetaminophen doesn’t exactly get a free pass. To the contrary, severe health problems such as liver damage and death have been reported, even after “mild” overdose.